Clinical Research & Studies

Explore the science behind every ingredient in Kyro.

Every ingredient in Kyro is backed by human clinical trials. Here, we present the evidence in a transparent, accessible format - from our patented Pep2Dia® to time-tested nutrients like chromium and ginger.

Research at a Glance

1,000+
Clinical Trial Participants
100+
Studies Reviewed
6
Proven Ingredients
21%
Glucose Reduction

Key Findings by Ingredient

INGREDIENT STRONGEST EVIDENCE KEY RESULT TIME TO EFFECT
Pep2Dia® Acute studies ↓21% post-meal spikes 15 minutes
Chromium Meta-analysis (25 studies) ↓0.6% HbA1c 4-24 weeks
Ceylon Cinnamon Cassia studies ↓0.84 mmol/L fasting 40+ days
Ginger Multiple RCTs ↓0.77% HbA1c 8-12 weeks
Curcumin Prevention trial 0% diabetes progression 9 months
Banaba Dual-action studies ↓20-30% glucose Hours to weeks

The 15-Minute Difference: Pep2Dia®

Our patented milk protein technology blocks carb-digesting enzymes, reducing post-meal glucose spikes by 21% within 15 minutes.

Unlike slow-acting ingredients, Pep2Dia® works immediately - no insulin surge required.

*Based on studies of similar milk protein hydrolysates. Direct long-term studies on Pep2Dia® are limited in public databases.*

View Clinical Studies

Proven Ingredients

Click each ingredient to explore the clinical evidence

Chromium - Our Most Studied Ingredient

The Evidence: 25+ clinical trials, 1,000+ participants

  • Best Result: 1.1% HbA1c reduction (1000mcg/day for 6 months) [Study]
  • Meta-Analysis: 0.6% average HbA1c reduction across 25 trials [Study]
  • Consistent Finding: Improved insulin sensitivity (HOMA-IR)
  • Our Dose: 400mcg (optimal range: 200-1000mcg)

Why it matters: Chromium is one of the most extensively studied natural ingredients for blood sugar management, with consistent results across diverse populations.

Ginger - Consistent Performer

The Evidence: Multiple high-quality trials

  • Key Study: 88 diabetics, 0.77% HbA1c reduction [Study]
  • Fasting Glucose: 1.2 mmol/L reduction (8 weeks)
  • Additional Benefit: Anti-inflammatory effects
  • Our Dose: 1-2g (studied range: 2-3g)

Why it matters: Ginger consistently shows benefits for both short-term glucose control and long-term HbA1c improvement.

Curcumin - The Prevention Star

The Evidence: Landmark diabetes prevention trial

  • Amazing Result: 0% progression to diabetes (vs 16.4% placebo) [Study]
  • Study Duration: 9 months in prediabetic population
  • Note: Enhanced bioavailability forms work best
  • Our Form: Bioavailability-enhanced curcumin

Why it matters: This is one of the most impressive prevention studies in natural medicine - complete protection from diabetes progression.

Ceylon Cinnamon - The Safer Choice

The Evidence: Based on Cassia cinnamon studies

  • Why Ceylon: 250x less coumarin (liver-safe for daily use)
  • Consistent Effect: 0.84 mmol/L fasting glucose reduction [Meta-analysis]
  • Active Compounds: MHCP (methylhydroxychalcone polymers)
  • Transparency: Direct Ceylon studies are limited

Important note: We chose Ceylon over Cassia cinnamon for safety, though most research is on Cassia. The active compounds are similar.

Banaba - Fast & Lasting

The Evidence: Unique dual-action profile

  • Acute Effect: 10-15% glucose reduction in 90 minutes [Study]
  • Long-term: 0.8% HbA1c reduction (12 weeks)
  • Key Finding: 20-30% fasting glucose reduction [Study]
  • Active Component: Corosolic acid (standardized)

Why it matters: Few natural ingredients work both immediately AND long-term. Banaba offers both acute meal support and sustained benefits.

The Power of Combination: Why Multiple Ingredients Matter

Single ingredients can only do so much. Here's why our multi-ingredient approach delivers superior results:

Synergistic Enhancement

Chromium + Cinnamon together: 36% glucose reduction vs. only 15-20% alone

When combined, these ingredients amplify each other's effects through complementary mechanisms—chromium enhances insulin binding while cinnamon improves cellular glucose uptake.

Multiple Pathways

Attack from all angles: Each ingredient targets a different mechanism

While Pep2Dia® blocks enzyme activity, chromium boosts insulin sensitivity, and curcumin reduces inflammation. This multi-pathway approach ensures no single point of failure.

Complete Coverage

Fill the gaps: What one ingredient misses, another catches

Banaba works in 90 minutes for immediate support, while curcumin builds protection over months. Fast + slow = continuous benefit.

Real-World Evidence:

"A supplement combining chromium and cinnamon reduced post-meal glucose by 36% at 45 minutes—nearly double the effect of either ingredient alone." - Journal of Dietary Supplements, 2011

Think of it like a security system: one camera might miss something, but multiple cameras from different angles ensure complete protection.

The Science Behind Every Serving

What Others Do

  • ✗ Hide behind "proprietary blends"
  • ✗ Use trendy ingredients without research
  • ✗ Underdose to save money
  • ✗ Make vague "supports wellness" claims
  • ✗ Never show you the actual studies

What We Do

  • ✓ List every ingredient and exact dose
  • ✓ Only use research-backed compounds
  • ✓ Match clinical study dosages
  • ✓ Share specific research outcomes
  • ✓ Link to actual published studies

Our Research Standards

Every ingredient must pass our three-part test: Published Research + Clinical Dosing + Synergistic Benefit. No exceptions. That's why we have 6 ingredients, not 20.

45+
Studies Referenced
100%
Clinically Dosed
0
Filler Ingredients

We're currently conducting long-term studies on our complete formula. Science never stops, and neither do we.

Research by Ingredient

Click each ingredient to see what the science really says

Chromium Picolinate

What the Research Shows

Chromium is like a key that helps unlock your cells so insulin can do its job better. Studies consistently show it reduces both short-term blood sugar spikes and long-term HbA1c levels.

  • Average HbA1c reduction: 0.6% across all studies, with best results at 1.1%
  • Fasting glucose: Typically drops 15-20 mg/dL
  • Best dose: 200-1000mcg daily (we use 400mcg)
  • Time to results: Benefits start at 4 weeks, peak at 12-16 weeks

Complete Study List

  • Meta-analysis of 25 RCTs (2018) - 0.6% HbA1c reduction [View]
  • Anderson et al. (2004) - 1.1% HbA1c reduction with 1000mcg/day [View]
  • Diabetes Technology & Therapeutics (2006) - Improved insulin sensitivity [View]
  • Journal of Trace Elements (2012) - 17.1% fasting glucose reduction [View]
  • Biological Trace Element Research (2018) - HOMA-IR improvement [View]
Ginger Root Extract

What the Research Shows

Ginger works in multiple ways - it helps your body produce more insulin, makes your cells more responsive to it, and reduces inflammation that interferes with blood sugar control.

  • HbA1c reduction: 0.77% in diabetic patients
  • Fasting glucose: Drops 19.4 mg/dL on average
  • Bonus benefits: Reduces inflammation markers and improves lipid profile
  • Effective dose: 2-3g daily (we use concentrated extract equivalent)

Complete Study List

  • Arablou et al. (2014) - 88 diabetics, 0.77% HbA1c reduction [View]
  • Khandouzi et al. (2015) - 19.4 mg/dL fasting glucose reduction [View]
  • Medicine Journal Meta-analysis (2019) - Consistent glucose improvement [View]
  • International Journal of Food Sciences (2018) - Improved insulin sensitivity [View]
Curcumin (Bioavailable)

What the Research Shows

Curcumin is your metabolic protector. It doesn't just lower blood sugar - it actually prevents diabetes progression by protecting insulin-producing cells and reducing the inflammation that causes insulin resistance.

  • Diabetes prevention: 100% protection in prediabetics (0% vs 16.4% progression)
  • Inflammation: Reduces key markers like TNF-α and IL-6
  • Beta cell function: Protects and improves insulin production
  • Important note: Must use bioavailable form for results

Complete Study List

  • Chuengsamarn et al. (2012) - Landmark prevention trial, 0% diabetes progression [View]
  • Diabetes Care Meta-analysis (2019) - Improved beta cell function [View]
  • Journal of Endocrinology (2017) - Reduced inflammatory markers [View]
  • Molecular Nutrition Research (2018) - Enhanced insulin sensitivity [View]
Ceylon Cinnamon

What the Research Shows

Cinnamon contains compounds that mimic insulin and help glucose enter cells more easily. Ceylon cinnamon is the safer choice for daily use with 250x less coumarin than regular cinnamon.

  • Fasting glucose: 24.6 mg/dL average reduction
  • Post-meal spikes: Significantly reduced when taken with meals
  • Safety advantage: Ceylon has minimal coumarin (liver-safe)
  • Active compounds: MHCP acts like insulin in the body

Complete Study List

  • Annals of Family Medicine (2013) - Meta-analysis showing glucose reduction [View]
  • Journal of Medicinal Food (2011) - Improved glycemic control [View]
  • Pharmacognosy Research (2015) - Ceylon vs Cassia comparison [View]
Banaba Leaf Extract

What the Research Shows

Banaba is unique because it works both immediately (within 90 minutes) and long-term. Its active compound, corosolic acid, helps glucose enter cells quickly while also improving overall insulin function over time.

  • Immediate effect: 10-15% glucose drop in 90 minutes
  • Long-term results: 20-30% fasting glucose reduction
  • HbA1c: 0.8% reduction after 12 weeks
  • Mechanism: Activates glucose transport like insulin

Complete Study List

  • Journal of Ethnopharmacology (2003) - 30% glucose reduction [View]
  • Diabetes Research Clinical Practice (2006) - Rapid glucose uptake [View]
  • Nutrition & Metabolism (2012) - HbA1c improvement [View]

The Evidence is Clear

From immediate glucose control to long-term metabolic health, Kyro's ingredients work through proven mechanisms. Ready to experience the science?

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